Forward or Backwards

Topics › Science › Medicine and Health

The Last Antibiotics: Can We Outrun Superbugs?

Published · 28 min

Watch on YouTube

Antibiotics made modern medicine safer. What happens as bacteria evade them? This video explains selection, mutation and plasmid transfer, how resistance spreads, and what the global death estimates actually measure.

Finally, NHS subscription payments and the proposed PASTEUR Act: how paying for availability could change antibiotic economics, and why global access remains contested. Sources checked 11 October 2026, including the September 2026 phage guideline. General medical and policy information, not individual treatment advice.

Historical photographs and colourised micrographs are credited on screen. Generated backgrounds are conceptual illustrations; none depict a named real person.

Educational documentary. Not financial or investment advice.

In these topics

Chapters

  1. The miracle running out
  2. Resistance, mechanically
  3. From patient to hospital to world
  4. Counting the dead
  5. Why the cure stops working
  6. The broken business model
  7. A pipeline running dry
  8. Can AI invent the next antibiotic?
  9. The virus that eats bacteria
  10. Paying for a cure to exist, not sell
  11. Resetting the clock

More from Forward or Backwards on YouTube

Sources and credits

Photo credits (Wikimedia Commons)

Primary sources

  • ACS/RSC penicillin history (1999)
  • CDC resistance mechanisms (31 Jan 2025) and spread (25 Sep 2025)
  • GRAM, Lancet: 2019 burden (20 Jan 2022) and 2021 burden (16 Sep 2024)
  • Access to Medicine Foundation, 2026 Benchmark (10 Mar 2026)
  • Achaogen SEC filings (2019); Novartis in Society 2018.
  • Swanson et al., Nature Machine Intelligence (2024); MIT / Cell (14 Aug 2025)
  • FDA gonorrhea approvals (12 Dec 2025)
  • Eliava Institute; Lederman/Bonomo (9 Feb 2026); Würstle et al., Nature Medicine (21 Sep 2026)
  • NICE AMR1/AMR2 (17 Aug 2022); NHS England procurement (12 Aug 2024)
  • PASTEUR Act of 2026, S.4875, introduced 23 Jun 2026; MSF response (30 Jun 2026)

Not regulated financial advice.